Quanxira Digital PCR： Fully Automated Digital PCR Platform

Introducing the Quanxiar Digital PCR Platform — a fully integrated, chip-based digital PCR system designed to deliver absolute quantification, ultra-high sensitivity, and scalable multiplexing for advanced research and clinical applications.

All-in-One Digital PCR — From Sample to Answer

Unlike conventional workflows, the system integrates:

• Sample loading

• Droplet generation in Chips

• PCR amplification

• Signal detection & analysis

into a single fully automated platform

✔ Minimal hands-on time (~1 minute preparation)

✔ Fully closed system — no manual transfer steps

✔ Reduced variability and improved reproducibility

Key Advantages

1. Absolute Quantification with Superior Sensitivity

• Absolute quantification without standard curves

• Detection of rare mutations

• No interference from wild-type background

2. Ultra-Multiplex Capability

Powered by Exponential Ultra-Multiplex Technology:

• Up to 63-plex detection in a single run

• Not limited by fluorescence channel count

• Enables high-density biomarker panels

3. AI-Driven Data Analysis

• Automated droplet classification

• Intelligent noise reduction

• High-confidence positive/negative calling

4. High-Stability Microfluidic Chip Technology

Our proprietary SS chip-based system features:

• 20,000 partitions per chip

• 95% effective droplet yield

• 99% droplet uniformity

Advantages:

• Superior stability vs droplet systems

• Minimal droplet fusion or loss

• Higher signal-to-noise ratio

5. Fully Automated Workflow

Hands-on time: ~1 minute

Total runtime: ~3–4 hours

Three simple steps:

• Load sample

• Start run

• Analyze results

System Performance

• Sensitivity: 0.01% detection level

• Dynamic range: 5 logs

• Precision: ±10%

• Throughput: 24 samples per run

• Fluorescence channels: up to 6+1 channels

Flexible Chemistry & Open System Compatibility

• Compatible with multiple PCR mixes

• Supports probe-based and dye-based assays

• Enables rapid assay development

Applications

1. Oncology & Precision Medicine

• Rare mutation detection

• MRD monitoring

• Tumor methylation analysis

2. Infectious Disease

• Respiratory pathogen panels

• Viral load quantification

• Multiplex pathogen detection

3. Biopharma & Cell/Gene Therapy

• Vector copy number

• Residual DNA detection

• QC for biologics

4. Neurology & Biomarkers

5. Environmental & Food Safety

Technology Comparison

Applications of Quanxira Digital PCR Platform

Proprietary SS Chip Technology

Engineered for Precision. Built for Performance.

At the core of the Quanxira™ digital PCR platform is a proprietary glass-based microfluidic chip architecture, designed to deliver superior thermal control, optical clarity, and partition consistency—enabling highly reliable digital quantification across a wide range of applications.

Advanced Sandwich-Structured(SS) Chip Design

Our chip features a patented glass-based sandwich structure, integrating microfluidic partitioning with optimized thermal and optical properties in a single platform.

Key capabilities include:

• >20,000 high-uniformity microwells per chip

• Enhanced thermal conductivity for improved reaction uniformity

• High optical transparency for superior signal detection

• Low background noise enabling higher signal-to-noise ratios

This architecture ensures consistent amplification conditions across all partitions, improving both quantification accuracy and reproducibility.

Superior Partition Integrity and Stability

Unlike traditional droplet-based systems, the SS Chip is engineered to support highly stable partitioning environments, minimizing variability introduced by droplet fusion or loss.

• ≥95% effective partition utilization

• ≥99% partition uniformity

• Reduced variability across runs and operators

This results in more statistically robust data and improved confidence in low-abundance target detection.

Designed for Multi-Modal Compatibility

The chip is built to support a broad range of assay chemistries, enabling seamless integration across different molecular workflows:

• Digital PCR (dPCR)

• Isothermal amplification

• Digital immuno-PCR and protein detection

This flexibility allows laboratories to expand beyond nucleic acid testing and adopt future-ready digital biology applications on a single platform.

Features comparison among ddPCR technologies:

Performance and System Specifications

Ordering Info: